Rare Association of a Rare Lymphoma
DOI:
https://doi.org/10.60591/crspmi.5Keywords:
Lymphohistiocytosis, Hemophagocytic, Lymphoma, Large B-Cell, Diffuse, PancytopeniaAbstract
Intravascular large B-cell lymphoma is a rare entity, characterized by growth of lymphoma cells in the lumina of small vessels of various organs. Its large clinical variability and difficulty in diagnosis leads to a poor prognosis, mainly if there is central nervous system involvement and/or it is an Asian variant associated with hemophagocytic syndrome. We present a 52-year-old Caucasian male admitted to investigate pancytopenia and B symptoms. After an extensive study, a liver nodule was biopsied and allowed the rare diagnosis of an Asian variant intravascular large B cell lymphoma. Intercurrent neurological involvement is a factor usually refractory to systemic chemotherapy.
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Copyright (c) 2023 Rodolfo Gomes, Joana Fiipa, Inês Mendes, Gonçalo Gerardo, Bárbara Sousa Picado, Fernando Martos Gonçalves
This work is licensed under a Creative Commons Attribution 4.0 International License.
