Paroxysmal Nocturnal Hemoglobinuria: An Unusual Suspect
DOI:
https://doi.org/10.60591/crspmi.284Keywords:
Hemoglobinuria, Paroxysmal/complications, Hemoglobinuria, Paroxysmal/diagnosis, Hemolysis, Pancytopenia, ThrombosisAbstract
Paroxysmal nocturnal hemoglobinuria (PNH) is a rare and underdiagnosed acquired hematopoietic stem cell disease, which can be revealed by intravascular hemolysis, thrombosis and secondary bone marrow failure. A delay on diagnosis could be due to a multiplicity of symptoms and clinical presentations, requiring a high clinical suspicion. The authors describe a case of PNH with a variety of clinical presentations, typical and atypical, leading to diagnosis. The increasing awareness of these presentations makes possible a future quickly identification and diagnosis of this rare condition.
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Copyright (c) 2025 Mariana Rita Mesquita Silva Estrela Santos, Raquel Dias Moura, Francisca Carmo, Paula Ferreira, Inês Rueff Rato
This work is licensed under a Creative Commons Attribution 4.0 International License.
