Nephrotic Syndrome as an Initial Manifestation of Secondary Syphilis: A Clinical Case
DOI:
https://doi.org/10.60591/crspmi.361Keywords:
Nephrotic Syndrome/etiology, Penicillin G/ therapeutic use, Syphilis/complicationsAbstract
Syphilis is a systemic disease with highly varied clinical presentations, caused by the spirochete Treponema pallidum. In the secondary stage of the disease, renal involvement can occur, with a prevalence ranging from 0.3% to 0.8%, and it can present in various forms. The association between secondary syphilis and nephrotic syndrome has been documented for several years and may even be the only manifestation of the infectious disease. In the presence of de novo nephrotic-range proteinuria in a patient with known risk factors, syphilis screening should be considered. The following clinical description reports a case of secondary syphilis with renal involvement, presenting initially as nephrotic syndrome.
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Copyright (c) 2025 Carolina Roias
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