Marine-Lenhart Syndrome: A Clinical Perspective and Diagnosis, About a Clinical Case

Authors

  • Juliana Carneiro Serviço Medicina Interna https://orcid.org/0009-0001-3078-9327
  • Renato Gonçalves Serviço Medicina Interna https://orcid.org/0000-0002-7849-6451
  • Carla Gonçalves Serviço Medicina Interna https://orcid.org/0000-0001-5028-8207
  • Ana Silva Serviço Medicina Interna, Unidade Local de Saúde Cova da Beira, Hospital Pêro da Covilhã, Covilhã, Portugal
  • Joana Coelho Serviço Medicina Interna, Unidade Local de Saúde Cova da Beira, Hospital Pêro da Covilhã, Covilhã, Portugal

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https://doi.org/10.60591/crspmi.176

Keywords:

Graves Disease, Hyperthyroidism, Thyroid Neoplasms, Thyroid Nodule

Abstract

Marine-Lenhart syndrome is a rare cause of hyperthyroidism, characterized by the coexistence of Graves' disease and a functioning nodule or toxic multinodular goiter. It has a prevalence of 0.8% to 2.7% in patients with severe disease, with few cases described in the literature. Here, we describe the case of a 67-year-old woman, with no relevant personal history, referred for symptomatic primary hyperthyroidism. Therapy with methimazole was initiated and a complementary study
was requested with thyroid scintigraphy with technetium- 99, which was suggestive of Marine-Lenhart syndrome. She was followed up in consultation and therapy with  symptomatic control and normalization of thyroid function. The authors will also review the existing literature on this rare syndrome.

 

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Published

2024-06-24

How to Cite

Carneiro, J., Gonçalves, R., Gonçalves, C., Silva, A., & Coelho, J. (2024). Marine-Lenhart Syndrome: A Clinical Perspective and Diagnosis, About a Clinical Case. SPMI Case Reports, 2(Edição Especial), 48–51. https://doi.org/10.60591/crspmi.176