Vipoma: A Rare Cause of Diarrhea

Authors

  • Jorge Silva Ferreira Serviço de Medicina I, Centro Hospitalar e Universitário de Lisboa Norte, Hospital de Santa Maria, Lisboa, Portugal
  • Maria Afonso Albuquerque Serviço de Saúde Ocupacional, Centro Hospitalar e Universitário de Lisboa Norte, Hospital de Santa Maria, Lisboa, Portugal
  • Maria Rosário Rosa Serviço de Cirurgia Geral, Centro Hospitalar e Universitário de Lisboa Norte, Hospital de Santa Maria, Lisboa, Portugal
  • Paula Alcântara Serviço de Medicina I, Centro Hospitalar e Universitário de Lisboa Norte, Hospital de Santa Maria, Lisboa, Portugal

DOI:

https://doi.org/10.60591/crspmi.10

Keywords:

Diarrhea, Duodenal Neoplasms, Neuroendocrine Tumors, Vipoma

Abstract

VIPoma is a rare neuroendocrine tumor (incidence 1:10 000 000), generally located in pancreas. This tumor is associated to increased risk of malignancy and secretes vasoactive intestinal peptide (VIP) resulting in the syndrome of watery diarrhea, hypokalemia, acidosis, hypochloridria and hypercalcemia. The only curative treatment is surgery.

We present the case of a 60-year-old male, admitted to the ward with vomiting and watery diarrhea, with 6-month duration. After detailed investigation, this case revealed to be due to a VIPoma located in duodenum. The authors underline the rarity of the diagnosis, its atypical location (extrapancreatic) and state the diagnostic difficulties due to fluctuating symptoms, locating the tumor and obtaining a definitive diagnosis.

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References

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Published

31-03-2023

How to Cite

Silva Ferreira, J., Afonso Albuquerque, M., Rosário Rosa, M., & Alcântara, P. (2023). Vipoma: A Rare Cause of Diarrhea. SPMI Case Reports, 1(1), 28–31. https://doi.org/10.60591/crspmi.10

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Section

Casos Clínicos

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