Vipoma: A Rare Cause of Diarrhea
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https://doi.org/10.60591/crspmi.10Keywords:
Diarrhea, Duodenal Neoplasms, Neuroendocrine Tumors, VipomaAbstract
VIPoma is a rare neuroendocrine tumor (incidence 1:10 000 000), generally located in pancreas. This tumor is associated to increased risk of malignancy and secretes vasoactive intestinal peptide (VIP) resulting in the syndrome of watery diarrhea, hypokalemia, acidosis, hypochloridria and hypercalcemia. The only curative treatment is surgery.
We present the case of a 60-year-old male, admitted to the ward with vomiting and watery diarrhea, with 6-month duration. After detailed investigation, this case revealed to be due to a VIPoma located in duodenum. The authors underline the rarity of the diagnosis, its atypical location (extrapancreatic) and state the diagnostic difficulties due to fluctuating symptoms, locating the tumor and obtaining a definitive diagnosis.
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