A Case of Hyperglycemia-Induced Seizures

Authors

  • Mafalda Sequeira Serviço de Medicina Interna, Hospital Garcia de Orta, Almada, Portugal
  • Bruno Sousa Serviço de Medicina Interna, Hospital Garcia de Orta, Almada, Portugal
  • Francisca Abecasis Serviço de Medicina Interna, Hospital Garcia de Orta, Almada, Portugal
  • Henrique Santos Serviço de Medicina Interna, Hospital Garcia de Orta, Almada, Portugal

##plugins.pubIds.doi.readerDisplayName##:

https://doi.org/10.60591/crspmi.33

Keywords:

Hyperglycemia/complications, Seizures/etiology

Abstract

Metabolic disorders, like hyperglycaemia, may be responsible for focal neurological alterations and should always be included in the differential diagnosis of seizures with subcortical T2 hypointensity and in fluid attenuated inversion recovery sequence (FLAIR), as well as restricted diffusion in apparent diffusion coefficient maps (ADC) on brain magnetic resonance imaging (MRI). The authors report a case of a 49-year-old man, with personal history of diabetes with poor metabolic control, admitted to hospital with seizures and focal neurological deficits caused, after extensive investigation, by hyperglycaemia. This case highlights the rarity of hyperglicemic-induced seizures in clinical practice and the need to consider less frequent aetiologies for seizures.

References

Acharya AB, Wroten M. Wernicke Aphasia. [Updated 2021 Aug 11]. In: StatPearls [Internet]. Treasure Island: StatPearls Publishing; 2022.

Javed K, Reddy V, M Das J, Wroten M. StatPearls [Internet]. Treasure Island: StatPearls; 2021.

Hiremath SB, Gautam AA, George PJ, Thomas A, Thomas R, Benjamin G. Hyperglycemia-induced seizures - Understanding the clinico- radiological association. Indian J Radiol Imaging. 2019;29:343-9. doi:10.4103/ijri.IJRI_344_19

Chen CC, Chai JW, Wu CH, Chen WS, Hung HC, Lee SK. Neuroimaging in seizure patients associated with nonketotic hyperglycemia. Neuroradiol J. 2011;24:215 20. doi: 10.1177/197140091102400208.

Jain A, Sankhe S. Hyperglycemia-induced seizures and blindness. Indian J Radiol Imaging. 2020;30:245-7. doi: 10.4103/ijri.IJRI_41_20.

Wang X, Yu H, Cai Z, Wang Z, Ma B, Zhang Y. Nonketotic hyperglycemia-related epileptic seizures. Epilepsy Behav Case Rep. 2013;1:77-8. doi: 10.1016/j.ebcr.2013.03.001.

Maccario M. Neurological dysfunction associated with nonketotic hyperglycemia. Arch Neurol. 1968;19:525-34. doi: 10.1001/archneur.1968.00480050095009.

Gorijala VK, Shaik L, Kowtha P, Kaur P, Nagarjunakonda VS. A Case Report of Nonketotic Hyperglycemic Seizures: A Diagnostic Dilemma. Cureus. 2020;12:e11416. doi: 10.7759/cureus.11416.

Downloads

Published

2023-11-29

How to Cite

Sequeira, M., Sousa, B., Abecasis, F., & Santos, H. (2023). A Case of Hyperglycemia-Induced Seizures. SPMI Case Reports, 1(4), 166–168. https://doi.org/10.60591/crspmi.33