Hepatic Angiosarcoma: A Case Report
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https://doi.org/10.60591/crspmi.20Keywords:
Hemangiosarcoma/diagnosis, Hemangiosarcoma/ diagnostic imaging, Hemangiosarcoma/pathology, Liver Neoplasms/diagnosis, Liver Neoplasms/diagnostic imaging, Liver Neoplasms/pathologyAbstract
Liver angiosarcoma is a rare vascular tumor within the group of malignant neoplasms of the liver. It does not present with specific signs / symptoms or tumor markers. It has a high mortality rate due to its aggressive nature. The authors describe the case of a 69 - years - old male patient presenting with significant weight loss, abdominal pain in the upper right quadrant, petechial lesions, rectal bleeding and epistaxis. Abdominal ultrasound showed multiple nodules and there was portal vein thrombosis and changes suggestive of multifocal hepatocarcinoma on abdominal computed tomography. Liver biopsy was conclusive for hepatic angiosarcoma.
In this case, unfortunately, the diagnosis was important
only in terms of excluding other pathologies, as it did
not allow any approach other than the institution of palliative measures, given the aggressiveness and rapid progression of the neoplasm in question.
References
Bhati CS, Bhatt AN , Starkeu G, Hubscher SG, Bramhall SR. Acute liver failure due to primary angiosarcoma: A case report and review of literature. World J Surg Oncol. 2008;6:104. doi: 10.1186/1477-7819-6-104.
Averbukh DL, Mavilia GM, Einstein MM. Hepatic Angiosarcoma: A challenging diagnosis. Cureus. 2018;10:3283. doi: 10.7759/cureus.3283.
Gen C, Li J, Wan R, Wang G, Shi J. Primary hepatic angiosarcoma in a 64-year-old man: A case report. Oncology letters. 2016;11:2445-8. doi: 10.3892/ol.2016.4277.
Chaudhary P, Bhadana U, Singh RAK, Ahuja A. Primary hepatic angiosarcoma. Eur J Surg Oncol. 2015;41:1137-43. doi: 10.1016/j.ejso.2015.04.022.
Marletta S, Cavallo E, Ammendola S, Stefanizzi L, Mastrosimini MG, D'Onofrio M, et al. Multifocal Hepatic Angiosarcoma with Atypical Presentation: Case Report and Literature Review. J Gastrointest Cancer. 2021;52:771-5.doi: 10.1007/s12029-020-00504-x.
Machuca LP, Chirinos OI, López Del Aguila J, Pflucker MV, Zacarías FC, et al. Hepatic angiosarcoma: case report and review of literature. Rev Gastroenterol Peru. 2012;32:317-22.
Loricera J, Calvo-Río V, Ortiz-Sanjuán F, González-López MA, Fernández-Llaca H, Rueda-Gotor J, et al. The Spectrum of Paraneoplastic Cutaneous Vasculitis in a Defined Population. Medicine. 2013;92:331-43. doi: 10.1097/MD.0000000000000009.
Koyama T, Fletcher J, Johnson C, Kuo M, Notohara K, Burgart L. Primary Hepatic Angiosarcoma: Findings at CT and MR Imaging. Radiology. 2002;222(:667-73. doi: 10.1148/radiol.2223010877.
Young RJ, Brown NJ, Reed MW, Hughes D, Wall P. Angiosarcoma. Lancet Oncol. 2010;11:507-14. doi: 10.1016/S1470-2045(10)70023-1.
Bernstock JS, Shafaat O, Hardigan A, Fox BM, Moore LS, Chagoya G, et al. Angiosarcoma of temporal bone: case report and review of the literature. World Neurosurg. 2019;130:351-7. doi: 10.1016/j.wneu.2019.07.107
