Hidradenitis Suppurativa: Two Successful Clinical Cases with Adalimumab
Hidradenite Supurativa: Dois Casos Clínicos de Sucesso sob Adalimumab
DOI:
https://doi.org/10.60591/crspmi.257Palavras-chave:
Adalimumab, Hidradenitis Suppurativa/diagnosis, Hidradenitis Suppurativa/therapyResumo
Hidradenitis suppurativa is a chronic inflammatory disease
that evolves in flares, characterized by painful nodules, abscesses, and fistulas, with a severe impact on patients' quality of life. Adalimumab is the first-line biological therapy in the treatment of severe hidradenitis suppurativa, preventing fistulasand scarring.
This article presents two cases of severe hidradenitis suppurativa. The first is a 29-year-old woman with no significant personal background, and the second is a 70-year-old man with multiple diseases. Both patients were diagnosed with severe hidradenitis suppurativa requiring hospitalization to control the disease, and showed significant clinical improvement with adalimumab.
This article aims to emphasize the importance of diagnostic
suspicion in patients of all genders and ages and highlights
the importance of an early therapy start, impacting the
disease’s prognostic and the patient's quality of life.
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Referências
Cabete J, Aparício Martins I. Recomendações na abordagem do doente com hidradenite supurativa. Acta Med Port. 2023;36:133-9. doi: 10.20344/amp.18916.
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Resumo das características do medicamento – Adalimumab [Internet]. 2017 [cited 2024 Feb 13]. Available from: https://ec.europa.eu/health/documents/community-register/2017/20170324137210/anx_137210_pt.pdf
Kimball AB, Okun MM, Williams DA, Gottlieb AB, Papp KA, Zouboulis CC, et al. Two phase 3 trials of adalimumab for hidradenitis suppurativa. N Engl J Med. 2016;375:422-34. doi: 10.1056/NEJMoa1504370
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Direitos de Autor (c) 2024 Mariana Quelhas, Daniela Nascimento Silva, Francine Mascarenhas de Moraes, José Manuel del Águila de los Ríos, Joaquina Dominguez
Este trabalho encontra-se publicado com a Creative Commons Atribuição-NãoComercial 4.0.