Arterial Hypertension: A Vicious Circle Clinical Case

Authors

  • Isabel Montenegro Araújo Serviço de Medicina, Hospital Beatriz Ângelo, Loures, Portugal
  • Inês Branco Carvalho Serviço de Medicina, Hospital Beatriz Ângelo, Loures, Portugal
  • Margarida Pimentel Nunes Serviço de Medicina, Hospital Beatriz Ângelo, Loures, Portugal
  • David Prescott Serviço de Medicina, Hospital Beatriz Ângelo, Loures, Portugal
  • Sofia Mateus Serviço de Medicina Interna, CUF – Torres Vedras, Torres Vedras, Portugal
  • António Martins Baptista Serviço de Medicina, Hospital Beatriz Ângelo, Loures, Portugal

DOI:

https://doi.org/10.60591/crspmi.71

Keywords:

Glycyrrhiza, Hypertension/chemically induced

Abstract

Hypertension is an important cardiovascular risk factor and is associated with high morbidity and mortality. About 10% of patients have secondary causes and the correct diagnosis is essential for the correct management of the patient.

 

This is the case of a 55-year-old previously healthy man, who presents with arterial hypertension difficult to manage during hospital admission, already with established kidney and cardiac injury. The etiological investigation highlighted the regular consumption of liquorice, raising the hypothesis of a hypertension secondary to liquorice. However, the established renal and cardiac lesions could not rule out an undiagnosed essential hypertension, exacerbated by liquorice.

 

Given the diagnosis of hypertension in a healthy patient, the etiological study and the investigation of target organ injury are essential. The correct clinical evaluation, with an exhaustive clinical history, and raising diagnostic hypothesis with a critical spirit continue to be the pillar of a correct medical evaluation.

Downloads

Download data is not yet available.

References

2018 ESC/ESH Guidelines for the management of arterial hypertension

Diaconu CC, Dediu GN, Iancu MA. Drug-induced arterial hypertension - a frequently ignored cause of secondary hypertension: a review. Acta Cardiol. 2018:1-7. doi: 10.1080/00015385.2017.1421445

Adamczak M, Wiecek A. Food Products That May Cause an Increase in Blood Pressure. Curr Hypertens Rep. 2020;22:2. doi: 10.1007/s11906-019-1007-y.

Varma R, Ross CN. Liquorice: a root cause of secondary hypertension. JRSM Open. 2017;8:2054270416685208. doi: 10.1177/2054270416685208.

Angus L, Stranks J. Natural liquorice-induced pseudoaldosteronism causing severe hypokalaemia, hypertension and rhabdomyolysis. Intern Med J. 2020;50:502-3. doi: 10.1111/imj.14796.

Penninkilampi R, Eslick EM, Eslick GD. The association between consistent licorice ingestion, hypertension and hypokalaemia: a systematic review and meta-analysis. J Hum Hypertens. 2017;31:699-707. doi: 10.1038/jhh.2017.45.

Luís Â, Domingues F, Pereira L. Metabolic changes after licorice consumption: A systematic review with meta-analysis and trial sequential analysis of clinical trials. Phytomedicine. 2018;39:17-24. doi: 10.1016/j.phymed.2017.12.010.

Catena C, Colussi G, Brosolo G, Verheyen N, Novello M, Bertin N, et al. Long-term renal and cardiac outcomes after stenting in patients with resistant hypertension and atherosclerotic renal artery stenosis. Kidney Blood Press Res. 2017;42:774-83. doi: 10.1159/000484299.

Meyrier A. Nephrosclerosis: a term in quest of a disease. Nephron. 2015;129:276-82. doi: 10.1159/000381195.

Seccia TM, Caroccia B, Calò LA. Hypertensive nephropathy. Moving from classic to emerging pathogenetic mechanisms. J Hypertens. 2017;35:205-12. doi: 10.1097/HJH.0000000000001170.

Meyrier A. Nephrosclerosis: update on a centenarian. Nephrol Dial Transplant. 2015;30:1833-41. doi: 10.1093/ndt/gfu366.

Published

2023-09-15

How to Cite

Montenegro Araújo , I., Branco Carvalho, I., Pimentel Nunes, M., Prescott, D., Mateus, S., & Martins Baptista, A. (2023). Arterial Hypertension: A Vicious Circle Clinical Case. SPMI Case Reports, 1(3), 119–121. https://doi.org/10.60591/crspmi.71

Issue

Section

Casos Clínicos

Categories