Kikuchi-Fujimoto Disease, a Rare Case of Lymphadenopaties
##plugins.pubIds.doi.readerDisplayName##:
https://doi.org/10.60591/crspmi.6Keywords:
Histiocytic Necrotizing Lymphadenitis, LymphadenopathyAbstract
Kikuchi-Fujimoto disease, or histiocytic necrotizing lymphadenitis, is a rare disease, of unknown cause. It is characterized by cervical lymphadenopathies and fever, and has usually a benign course. Its diagnosis is based on histopathologic examination, and it is important to distinguish from infectious and lymphoproliferative disorders that are clinically similar but with completely different treatment and prognosis. Besides that, it is important to be aware of its association with autoimmune diseases, namely systemic lupus erythematosus.
We report a clinical case of a young woman with fever and right supraclavicular lymphadenopathies, admitted with the suspicion of a lymphoproliferative syndrome, whose biopsy revealed this condition.
References
Gonçalves M, Silva G, Barros A, Freitas L, Caldeira P, Rodrigues R, et al. Doença de Kikuchi-Fujimoto e Lúpus Eritematoso sistémico. Rev Soc Port Med Interna. 2008: 112-16
Moreira A, Louro F, Martins M, Duarte AP. Doença de Kikuchi e Fujimoto. Acta Med Port. 2000;13:43-7.
Reichert A, Correia T, Freitas O, Almeida, T, Rosado L. Doença de Kikuchi e Fujimoto. Acta Med Port. 2005;18:231-4.
Pina R, Fonseca I, Saldanha M. Doença de Kikuchi-Fujimoto: Uma causa pouco frequente de adenopatias cervicais. Rev Soc Port Med Interna. 2004: 11: 187-90.
Antunes I, Botella A, Marques F, Araújo I, Abreu A, Cardiga R, et al. Dilemas de diagnóstico de linfadenite necrotizante (doença de Kikuchi-Fujimoto). Acta Med Port. 2011;24 Suppl 3:681-4.
Mathew LM, Kapila R, Schwartz RA. Kikuchi-Fujimoto disease: a diagnostic dilemma. Int J Dermatol. 2016;55:1069-75. doi: 10.1111/ijd.13314.
Perry AM, Choi SM. Kikuchi-Fujimoto Disease: A Review. Arch Pathol Lab Med. 2018;142:1341-6. doi: 10.5858/arpa.2018-0219-RA.
Cuervo J, Dandin P, Castiglioni T, Ortega L, Amaral D, Faifman R. Enfermedad de Kikuchi-Fujimoto - Presentación de un caso clínico. Arch Argent Pediatr. 2008: 106:533-51.
Ifeacho S, Aung T, Akisnola M. Kikuchi-Fujimoto Disease: A case report and review of the literature. Cases J. 2008: 1:187.
Xavier R, Sila D, Keiserman M, Lopes M. Kikuchi-Fujimoto disease. J Bras Pneumol. 2008: 34:1074-8. doi: 10.1590/s1806-37132008001200014.
Santana A, Lessa B, Galrão L, Lima I, Santiago M. Kikuchi-Fujimoto's disease associated with systemic lupus erythematosus: case report and review of the literature. Clin Rheumatol. 2005: 24:60-3. doi: 10.1007/s10067-004-0923-6.
el-Ramahi KM, Karrar A, Ali MA. Kikuchi disease and its association with systemic lupus erythematosus. Lupus. 1994;3:409-11. doi: 10.1177/096120339400300508.
