Vascular Liver Diseases and Portal Hypertension Management in Pregnancy: A Clinical Case

Authors

  • Filipe Andrade Department of Medicine, Hospital Pedro Hispano, Matosinhos, Portugal; Service d’Hépatologie, DHU Unity, Hôpital Beaujon, Assistance Publique-Hôpitaux de Paris, Clichy, France https://orcid.org/0000-0002-9408-2240

DOI:

https://doi.org/10.60591/crspmi.568

Keywords:

Esophageal and Gastric Varices, Hypertension, Portal, Portal Vein, Portasystemic Shunt, Transjugular Intrahepatic, Pregnancy Complications, Pregnancy Outcome, Venous Thrombosis

Abstract

Pregnancy in women with portal hypertension carries maternal and foetal risks. We report a case of a woman with porto-sinusoidal vascular disorder (PSVD) and partial portal vein thrombosis, who developed variceal bleeding during pregnancy. Haemorrhage was refractory to endoscopic treatment and required placement of a transjugular intrahepatic portosystemic shunt (TIPS), the pregnancy continued and resulted in the delivery of a healthy infant at 38 weeks. Long-term follow-up confirmed TIPS patency, and the patient subsequently had two further pregnancies. This case highlights the challenges of managing portal hypertension in pregnancy, the role of TIPS, and the importance of individualized thrombotic and haemorrhagic risk assessment.

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References

1. Bissonnette J, Durand F, de Raucourt E, Ceccaldi PF, Plessier A, Valla D, et al. Pregnancy and vascular liver disease. J Clin Exp Hepatol. 2015;5:41-50. doi:10.1016/j.jceh.2014.12.007

2. European Association for the Study of the Liver. EASL Clinical Practice Guidelines on the management of liver diseases in pregnancy. J Hepatol. 2023;79:768-828. doi:10.1016/j.jhep.2023.03.006

3. Andrade F, Shukla A, Bureau C, Senzolo M, D'Alteroche L, Heurgué A, et al. Pregnancy in idiopathic non-cirrhotic portal hypertension: A multicentric study on maternal and fetal management and outcome. J Hepatol. 2018;69:1242-9. doi:10.1016/j.jhep.2018.08.007

4. Aggarwal N, Sawhney H, Vasishta K, Dhiman RK, Chawla Y. Non-cirrhotic portal hypertension in pregnancy. Int J Gynaecol Obstet. 2001;72:1-7. doi: 10.1016/s0020-7292(00)00263-0.

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Published

15-04-2026

How to Cite

Andrade, F. (2026). Vascular Liver Diseases and Portal Hypertension Management in Pregnancy: A Clinical Case. SPMI Case Reports, 4(Special Issue), 46–47. https://doi.org/10.60591/crspmi.568

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